The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2024
Filed:
Dec. 02, 2019
Alberto Gandini, Katy, TX (US);
James F. Antaki, Ithaca, NY (US);
Byron Wang Chuan, Pittsburgh, PA (US);
Joie N. Marhefka, Pittsburgh, PA (US);
Juha-pekka Mattila, Pearland, TX (US);
Eliseo Salas, Stone Mountain, GA (US);
Alberto Gandini, Katy, TX (US);
James F. Antaki, Ithaca, NY (US);
Byron Wang Chuan, Pittsburgh, PA (US);
Joie N. Marhefka, Pittsburgh, PA (US);
Juha-Pekka Mattila, Pearland, TX (US);
Eliseo Salas, Stone Mountain, GA (US);
CARNEGIE MELLON UNIVERSITY, Pittsburgh, PA (US);
Abstract
The present invention provides microfluidic pScreen™ devices for quantifying the concentration of DNA fragments in a liquid sample by using magnetic-responsive silica micro-beads and nonmagnetic-responsive silica micro-beads. The devices of the present invention allow for rapid, simple and inexpensive quantification of DNA fragment concentration in a sample. The devices do not require complex instrumentation and can be performed in less than three minutes. Moreover, they are compatible with complex samples including, without limitation, unpurified PCR amplification products, and thus can be expected to seamlessly integrate into various common molecular biology techniques and workflows.