The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2024
Filed:
Oct. 29, 2020
Applicant:
Johnson & Johnson Consumer Inc., Skillman, NJ (US);
Inventors:
Nicolas Joly-Tonetti, Suisse, CH;
Thomas Ondet, Val de Reuil, FR;
Mario Monshouwer, Beerse, BE;
Georgios N. Stamatas, Val de Reuil, FR;
Assignee:
Johnson & Johnson Consumer Inc., Skillman, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
G01N 33/5014 (2013.01); G01N 33/5044 (2013.01); C12N 5/0629 (2013.01); C12N 2503/02 (2013.01); C12N 2513/00 (2013.01);
Abstract
An epidermal tridimensional model exhibiting differentiating keratinocytes in a reconstituted stratum corneum model is disclosed. The model, which contains a cancer therapeutic at an amount effective to simulate chronic drug exposure, can be used to evaluate the potential of cancer therapeutics to produce skin related side effects. The method can also be used to evaluate the efficacy of a composition in reducing the effects of cancer therapeutics on skin.