The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2024

Filed:

Aug. 19, 2021
Applicant:

Emory University, Atlanta, GA (US);

Inventors:

Frances Eun-Hyung Lee, Atlanta, GA (US);

Ignacio Sanz, Atlanta, GA (US);

Doan Nguyen, Atlanta, GA (US);

Assignee:

Emory University, Atlanta, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0781 (2010.01); A61K 35/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0635 (2013.01); A61K 35/00 (2013.01); C12N 2500/02 (2013.01); C12N 2500/32 (2013.01); C12N 2500/34 (2013.01); C12N 2500/38 (2013.01); C12N 2500/60 (2013.01); C12N 2501/2305 (2013.01); C12N 2501/2306 (2013.01); C12N 2501/2321 (2013.01); C12N 2501/24 (2013.01); C12N 2501/25 (2013.01); C12N 2501/998 (2013.01); C12N 2502/1358 (2013.01); C12N 2533/52 (2013.01);
Abstract

This disclosure relates to growth media and environments for in vitro culturing of cells that produce or are capable of producing antibodies. In certain embodiments, the media comprises IL-6, fibronectin, and typically a saccharide. In certain embodiments, the disclosure contemplates cell culture compositions comprising IL-6 and fibronectin that are derived from proteins secreted from mesenchymal stromal/stem cells (MSCs). In certain embodiments, the disclosure contemplates enclosures comprising culture compositions disclosed herein that are in ambient air or optionally in an environment wherein oxygen is absent or at a low concentration.


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