The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2024

Filed:

Mar. 16, 2020
Applicants:

David A. Wolf, Houston, TX (US);

Alvin T. Rockhill, Akron, OH (US);

William H. Beeson, Carmel, IN (US);

Tammy Wolf, Houston, TX (US);

Inventors:

David A. Wolf, Houston, TX (US);

Alvin T. Rockhill, Akron, OH (US);

William H. Beeson, Carmel, IN (US);

Tammy Wolf, Houston, TX (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/075 (2010.01); C12M 3/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0609 (2013.01); C12M 21/06 (2013.01); C12N 2500/32 (2013.01); C12N 2501/01 (2013.01);
Abstract

A highly effective technique for fertilizing an oocyte with a sperm cell to produce a zygote can be carried out in a bioreactor and the zygote can optionally be cultured in the bioreactor into a blastocyst stage embryo for implantation into the uterus of a female recipient. The success rate and probability of fertilization is enhanced by operating the bioreactor reactor under conditions of inter-galactic motion which increases the probability of the sperm coming in close proximity to and fertilizing the oocyte. This method involves the steps of collecting an oocyte from a female donor, collecting sperm from a male donor, fertilizing the oocyte with the sperm in a rotating bioreactor to produce a zygote, culturing the zygote into a blastocyst stage embryo, and implanting the blastocyst stage embryo into a uterus of a recipient female.


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