The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2024
Filed:
Jan. 19, 2024
Applicant:
Napigen, Inc., Wilmington, DE (US);
Inventors:
Hajime Sakai, Newark, DE (US);
Byung-Chun Yoo, Newark, DE (US);
Emil Meyer Orozco, Jr., Cochranville, PA (US);
Ganesh Kishore, St. Louis, MO (US);
Narendra Singh Yadav, Wilmington, DE (US);
Assignee:
NAPIGEN, INC., Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C12N 9/22 (2006.01); C12N 15/10 (2006.01); C12N 15/113 (2010.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8213 (2013.01); C12N 9/22 (2013.01); C12N 15/102 (2013.01); C12N 15/113 (2013.01); C12N 15/63 (2013.01); C12N 15/8289 (2013.01); C12N 2310/20 (2017.05); C12N 2310/3513 (2013.01); C12Y 207/07049 (2013.01);
Abstract
Provided herein are methods and systems for altering the genome of an organelle. In some embodiments, the method comprises introducing into an organelle a recombinant DNA construct comprising a first polynucleotide encoding at least one guide RNA and a second polynucleotide encoding a polynucleotide guided polypeptide; and growing a cell comprising the organelle under conditions in which the first polynucleotide and the second polynucleotide are each expressed.