The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2024

Filed:

Aug. 10, 2022
Applicants:

Lanxess Corporation, Pittsburgh, PA (US);

The Penn State Research Foundation, University Park, PA (US);

Inventors:

Bei Yin, Wilmington, DE (US);

Thomas K. Wood, Port Matilda, PA (US);

Assignees:

LANXESS Corporation, Pittsburgh, PA (US);

The Penn State Research Foundation, University Park, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/74 (2006.01); C12Q 1/02 (2006.01); C12Q 1/18 (2006.01);
U.S. Cl.
CPC ...
C12N 15/74 (2013.01); C12Q 1/025 (2013.01); C12Q 1/18 (2013.01);
Abstract

Methods of controlling bacteria cells are disclosed. These methods comprise upregulating expression of a DVU2956 sigma 54-dependent enhancer-binding protein (EBP) in bacteria cells, resulting in (i) dispersing a biofilm of the cells or reducing biofilm formation by the cells, and/or (ii) reducing hydrogen sulfide formation by the cells. Further disclosed are methods of identifying compounds for controlling bacteria cells as in (i) and/or (ii) above. Polynucleotides and cells are disclosed that can optionally be used to practice compound identification methods.


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