The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2024

Filed:

Oct. 19, 2018
Applicants:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Fondazione Ri.med, Palermo, IT;

Inventors:

Davide Marino, Paternò, IT;

Riccardo Gottardi, Pittsburgh, PA (US);

Rocky Sung Chi Tuan, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/42 (2006.01); C12M 1/00 (2006.01); C12M 1/02 (2006.01); C12M 1/12 (2006.01); C12M 1/32 (2006.01); C12M 1/34 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12M 35/04 (2013.01); C12M 23/12 (2013.01); C12M 23/38 (2013.01); C12M 27/00 (2013.01); C12M 37/04 (2013.01); C12M 41/12 (2013.01); C12M 41/34 (2013.01); B01L 2400/0478 (2013.01); C12N 5/0068 (2013.01);
Abstract

Disclosed mechanical stimulator systems can maintain the sterility of biological samples within a multi-well plate while mechanically stimulating the samples. The systems disclosed herein allow for the individual activation by mechanical compression of a high number of samples at the same time, while maintaining sterility of the samples. The well plates, guides, actuators, pistons, and other components of the disclosed systems can be configured to be contained in or adjacent to an incubator that can control properties such as gas levels and temperature while at the same time allowing for the mechanical actuation of the biological samples.


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