The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2024
Filed:
Dec. 19, 2014
President and Fellows of Harvard College, Cambridge, MA (US);
Jose Fernandez-alcon, Cambridge, MA (US);
Norman Wen, Newton, MA (US);
Richard Novak, Jamaica Plain, MA (US);
Jose Fernandez-Alcon, Cambridge, MA (US);
Norman Wen, Newton, MA (US);
Richard Novak, Jamaica Plain, MA (US);
Donald E. Ingber, Boston, MA (US);
Geraldine A. Hamilton, Cambridge, MA (US);
Christopher Hinojosa, Cambridge, MA (US);
Karel Domansky, Charlestown, MA (US);
Daniel Levner, Cambridge, MA (US);
Guy Thompson, II, Lexington, MA (US);
Kambez Hajipouran Benam, Cambridge, MA (US);
Remi Villenave, Boston, MA (US);
Thomas Umundum, Salzburg, AT;
Alfred Paris, Salzburg, AT;
Georg Bauer, Salzburg, AT;
PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US);
Abstract
An organomimetic device includes a microfluidic device that can be used to culture cells in its microfluidic channels. The organomimetic device can be part of dynamic system that can apply mechanical forces to the cells by modulating the microfluidic device and the flow of fluid through the microfluidic channels. The membrane in the organomimetic device can be modulated mechanically via pneumatic means and/or mechanical means. The organomimetic device can be manufactured by the fabrication of individual components separately, for example, as individual layers that can be subsequently laminated together.