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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12173073 B1

PDFFull Text
Date of Patent:
Dec. 24, 2024

Filed:

Dec. 27, 2022

Methods of treatment by targeting vcam1 and maea

Applicant:

Albert Einstein College of Medicine, Bronx, NY (US);

Inventors:

Paul S. Frenette, Bronx, NY (US);

Sandra Pinho, Bronx, NY (US);

Qiaozhi Wei, Bronx, NY (US);

Sung Kyun Lee, Bronx, NY (US);

Assignee:

ALBERT EINSTEIN COLLEGE OF MEDICINE, Bronx, NY (US);

Attorney:

Perkins Coie LLP

Primary Examiner:

Maher M Haddad

Int. Cl.
CPC ...
C07K 16/00 (2006.01); A61K 39/395 (2006.01); A61P 7/00 (2006.01); A61P 35/02 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C07K 16/46 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2836 (2013.01); A61K 39/3955 (2013.01); A61P 7/00 (2018.01); A61P 35/02 (2018.01); C07K 16/18 (2013.01); C07K 16/2821 (2013.01); C07K 16/2878 (2013.01); C07K 16/2896 (2013.01); C07K 16/3061 (2013.01); A61K 2039/505 (2013.01); A61K 45/06 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01);
Abstract

Antibodies and antibody fragments that inhibit the activity of vascular cell adhesion molecule 1 (VCAM1) and/or macrophage erythroblast attacher (MAEA) are provided, along with formulations and kits comprising these antibodies and antibody fragments and the use of the disclosed compositions, formulations, and kits to treat cancers, sickle cell disease, and Polycythemia Vera.

Find Patent Forward Citations

Frenette, Paul. (2024). Methods of treatment by targeting vcam1 and maea (U.S. Patent No. 12173073). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12173073

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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