The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2024

Filed:

Aug. 10, 2021
Applicants:

Genentech, Inc., South San Francisco, CA (US);

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Ngiap-Kie Lim, Dublin, CA (US);

Jeff Shen, Foster City, CA (US);

Lauren Elizabeth Sirois, San Francisco, CA (US);

Jacob C. Timmerman, San Mateo, CA (US);

Etienne Trachsel, Basel, CH;

Nicholas Andrew White, San Francisco, CA (US);

Jie Xu, San Mateo, CA (US);

Haiming Zhang, San Mateo, CA (US);

Stephan Bachmann, Allschwil, CH;

Raphael Bigler, Basel, CH;

Kyle Bradley Pascual Clagg, San Francisco, CA (US);

Antonio Giovanni Dipasquale, San Bruno, CA (US);

Francis Gosselin, San Mateo, CA (US);

Ugo Jonathan Orcel, Basel, CH;

Roland Christoph Meier, Basel, CH;

Assignees:

Genentech, Inc., South San Francisco, CA (US);

Hoffmann-La Roche Inc., Little Falls, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01);
Abstract

Provided herein are methods of synthesizing quinazoline compounds comprising at least one atropisomeric center.


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