The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2024

Filed:

Mar. 12, 2020
Applicant:

Council of Scientific and Industrial Research, New Delhi, IN;

Inventors:

Chandrasekhar Srivari, Hyderabad, IN;

Satyendra Mainkar Prathama, Hyderabad, IN;

Kranthi Kumar Ramagonolla, Hyderabad, IN;

Sukumar Genji, Hyderabad, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 213/08 (2006.01); C07C 213/00 (2006.01); C07D 335/02 (2006.01);
U.S. Cl.
CPC ...
C07C 213/08 (2013.01); C07C 213/00 (2013.01); C07D 335/02 (2013.01);
Abstract

The present invention relates to a process for the preparation of tapentadol and analogs or compounds or stereoisomers of formula (I), Formula I wherein, A is aryl, heteroaryl, and cycloalkyl; R is H, OH, OR, halogen, C-Calkyl, cycloalkyl, aryl or heteroaryl; Ris C-Calkyl, cycloalkyl, aryl or heteroaryl, wherein each of these groups may further be substituted with one or more substituent selected from H, OH, halogen, CN, NO, C-Calkyl or phenyl. Further, the multi-step process involves no column chromatography purification until the very last step. This makes this process highly commercially viable and industrially useful.


Find Patent Forward Citations

Loading…