The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2024

Filed:

Feb. 06, 2021
Applicant:

The University of British Columbia, Vancouver, CA;

Inventors:

Veronika Schmitt, Vancouver, CA;

John K. Jackson, West Vancouver, CA;

Martin E. Gleave, Vancouver, CA;

Claudia Kesch, Essen, DE;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); A61K 9/00 (2006.01); A61K 31/337 (2006.01); A61K 31/7068 (2006.01); A61K 47/10 (2017.01); A61K 47/32 (2006.01); A61K 47/36 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 9/0034 (2013.01); A61K 31/337 (2013.01); A61K 31/7068 (2013.01); A61K 47/10 (2013.01); A61K 47/32 (2013.01); A61K 47/36 (2013.01);
Abstract

This invention provides compositions for controlled localized depositing of one or more drugs within a subject. More particularly, described herein are compositions comprising a) a polyethylene glycol (PEG) composition having a first low molecular weight PEG (Mw between 200-500 Da) and a second low molecular weight PEG (Mw between 500-2000 Da) and b) a mucoadhesive in polymer. Alternatively, composition may comprise a) a polyethylene glycol (PEG) composition having a first low molecular weight PEG (Mw between 200-500 Da) and a second low molecular weight PEG (Mw between 500-2000 Da), b) a water insoluble polymer and c) a mucoadhesive polymer. Furthermore, the composition may further comprise one or more drugs. Also provided are methods of manufacturing and administering the compositions described herein, which are used as biodegradable, injectable mucoadhesive low-viscosity pastes.


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