The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2024
Filed:
Dec. 11, 2023
Applicant:
Urogen Pharma Ltd., Ra'anana, IL;
Inventors:
Assignee:
UROGEN PHARMA LTD., Ra'anana, IL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/407 (2006.01); A61K 9/06 (2006.01); A61K 47/10 (2017.01); A61K 47/18 (2017.01); A61K 47/38 (2006.01);
U.S. Cl.
CPC ...
A61K 31/407 (2013.01); A61K 9/06 (2013.01); A61K 47/10 (2013.01); A61K 47/18 (2013.01); A61K 47/38 (2013.01);
Abstract
Pharmaceutical compositions and methods for sustained release of therapeutic agents for local treatment of cancer diseases involve embedding lyophilized mitomycin C in a slowly releasing biocompatible hydrogel applied to affected tissue. The mitomycin C is lyophilized in a composition using urea as a bulking agent, and the mitomycin C and the bulking agent are present in a ratio of from about 1:7 to about 1:9 in the lyophilized pharmaceutical composition.