The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2024

Filed:

Sep. 27, 2023
Applicant:

Boulder Bioscience Llc, Boulder, CO (US);

Inventors:

Michael A. Zeligs, Boulder, CO (US);

Irwin C. Jacobs, Defiance, MO (US);

Assignee:

Boulder BioScience LLC, Boulder, CO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/404 (2006.01); A61K 45/06 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/404 (2013.01); A61K 45/06 (2013.01); A61P 25/00 (2018.01);
Abstract

Provided herein are methods of treating non-hemorrhagic closed head injury (NHCHI) with 3,3'-diindolylmethane or an analog thereof. In one embodiment, NHCHI covers Traumatic Brain Injuries (TBIs) including mild to severe concussion, blast injury due to proximity to explosions, cerebral contusion, coup-contrecoup injury, DAI, Second Impact Syndrome, or CHI associated with deceleration injury.


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