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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12168781 B1

PDFFull Text
Date of Patent:
Dec. 17, 2024

Filed:

Dec. 06, 2019

Production method for t cells or nk cells, medium for culturing t cells or nk cells, method for culturing t cells or nk cells, method for maintaining undifferentiated state of undifferentiated t cells, and growth-accelerating agent for t cells or nk cells

Applicants:

Kirin Holdings Kabushiki Kaisha, Tokyo, JP;

Kyoto University, Kyoto, JP;

Inventors:

Shinichiro Takayanagi, Tokyo, JP;

Atsushi Kunisato, Tokyo, JP;

Sayaka Chuganji, Tokyo, JP;

Ken Fukumoto, Tokyo, JP;

Kazuki Nakazono, Tokyo, JP;

Shin Kaneko, Kyoto, JP;

Yohei Kawai, Kyoto, JP;

Assignees:

KIRIN HOLDINGS KABUSHIKI KAISHA, Tokyo, JP;

Kyoto University, Kyoto, JP;

Attorney:

Foley & Lardner LLP

Primary Examiner:

Eric Olson

Assistant Examiner:

Benjamin M Brandsen

Int. Cl.
CPC ...
C12N 5/0783 (2010.01); C07D 215/00 (2006.01); C07D 217/22 (2006.01); C07D 471/18 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0646 (2013.01); C07D 215/00 (2013.01); C07D 217/22 (2013.01); C07D 471/18 (2013.01); C12N 5/0637 (2013.01); C12N 2501/48 (2013.01); C12N 2501/999 (2013.01);
Abstract

The present invention relates to a method for producing T cells or NK cells including culturing T cells or NK cells in a culture medium containing a CaMKII inhibitor such as a bisbenzylisoquinoline alkaloid compound. The disclosed compounds and methods can be used for maintaining the undifferentiated state of undifferentiated T cells, or for efficiently proliferating T cells or NK cells.

Find Patent Forward Citations

Takayanagi, Shinichiro. (2024). Production method for t cells or nk cells, medium for culturing t cells or nk cells, method for culturing t cells or nk cells, method for maintaining undifferentiated state of undifferentiated t cells, and growth-accelerating agent for t cells or nk cells (U.S. Patent No. 12168781). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12168781

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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