The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2024
Filed:
Dec. 28, 2021
Applicant:
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Inventors:
Tomoyuki Igawa, Shizuoka, JP;
Yuri Teranishi, Shizuoka, JP;
Assignee:
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/36 (2006.01);
U.S. Cl.
CPC ...
C07K 16/36 (2013.01); C07K 2317/526 (2013.01); C07K 2317/53 (2013.01);
Abstract
As a result of producing ACE910 variants in which various sites of the constant regions were modified, the inventors discovered bispecific antibodies having FVIII mimetic activity higher than that of ACE910. The inventors also identified mutation positions that elevate the FVIII mimetic activity and discovered methods for elevating the FVIII mimetic activity by using the mutations.
Igawa, Tomoyuki. (2024). Bispecific antibodies which bind blood coagulation factor viii and have enhanced activity, and methods of use thereof for treating bleeding and associated conditions (U.S. Patent No. 12168697). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12168697
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile