The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 17, 2024

Filed:

Jan. 25, 2021
Applicants:

Guangdong Lewwin Pharmaceutical Research Institute Co., Ltd., Guangdong, CN;

Guangdong Cs-lewwin Drug Research Co., Ltd., Guangdong, CN;

Inventors:

Xingshu Li, Guangdong, CN;

Xinzi Chen, Guangdong, CN;

Wei Yang, Guangdong, CN;

Jianmin Guo, Guangdong, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/10 (2006.01); A61K 31/4545 (2006.01); A61P 35/00 (2006.01); C07B 59/00 (2006.01); C07D 239/30 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/10 (2013.01); A61P 35/00 (2018.01); C07B 59/002 (2013.01); C07D 239/30 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07B 2200/05 (2013.01);
Abstract

The present invention discloses a pyrimidine derivative containing one deuterium atom, a preparation process thereof and a use thereof. It is demonstrated through in vivo and in vitro animal experiments that the antitumor activity of the pyrimidine derivative containing one deuterium atom provided in the disclosure is significantly superior to that of the positive drug Tepotinib, and the preparation process is simple and low in cost.


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