The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2024
Filed:
Mar. 27, 2019
Applicant:
The Curators of the University of Missouri, Columbia, MO (US);
Inventors:
George R. Kracke, Columbia, MO (US);
Lalit N. Goswami, Columbia, MO (US);
Marion F Hawthorne, Columbia, MO (US);
Satish S. Jalisatgi, Columbia, MO (US);
Assignee:
The Curators of the University of Missouri, Columbia, MO (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/08 (2006.01); A61P 21/00 (2006.01); C07C 211/63 (2006.01);
U.S. Cl.
CPC ...
C07D 401/08 (2013.01); A61P 21/00 (2018.01); C07C 211/63 (2013.01);
Abstract
Disclosed herein are carborane derivatives of Formula I or Formula V, or a pharmaceutically acceptable salt thereof, for use as neuromuscular blocking agents. The carborane is substituted with two cationic functional groups selected from amines that form ammonium cations, ethers and/or alcohols that form oxonium cations, sulfides and/or thiols that form sulfonium cations, and phosphanes and/or phosphines that form phosphonium cations.