The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2024
Filed:
Feb. 05, 2024
Applicant:
Nexys Therapeutics, Inc., San Diego, CA (US);
Inventors:
Tom Yao-Hsiang Wu, San Diego, CA (US);
Qihui Jin, San Diego, CA (US);
Assignee:
NEXYS THERAPEUTICS, INC., San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/42 (2006.01); A61K 31/505 (2006.01); A61K 31/655 (2006.01); A61K 31/675 (2006.01); C07F 9/6512 (2006.01);
U.S. Cl.
CPC ...
C07D 239/42 (2013.01); A61K 31/505 (2013.01); A61K 31/655 (2013.01); A61K 31/675 (2013.01); C07F 9/6512 (2013.01);
Abstract
The present invention relates to pharmaceutical compounds of Formula (I): as further described herein, and pharmaceutical compositions containing such compounds, as well as methods of using these compounds to modulate the activity of aryl hydrocarbon receptor (AhR) and to treat conditions comprising inflammation inside the intestinal tract and certain disorders of the central nervous system affected by the gut-brain axis, including IBD, ulcerative colitis, Crohn's disease, Huntington's disease, and multiple sclerosis.