The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 17, 2024

Filed:

Jun. 14, 2021
Applicant:

Medizinische Hochschule Hannover, Hannover, DE;

Inventors:

Thomas Aper, Hannover, DE;

Mathias Wilhelmi, Isernhagen, DE;

Axel Haverich, Hannover, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/26 (2006.01); A61L 27/22 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 31/04 (2006.01); A61L 33/00 (2006.01); A61L 33/08 (2006.01);
U.S. Cl.
CPC ...
A61L 27/26 (2013.01); A61L 27/225 (2013.01); A61L 27/507 (2013.01); A61L 27/54 (2013.01); A61L 31/046 (2013.01); A61L 33/0011 (2013.01); A61L 33/08 (2013.01); A61L 2300/236 (2013.01); A61L 2300/252 (2013.01); A61L 2300/254 (2013.01); A61L 2300/418 (2013.01); A61L 2300/42 (2013.01); A61L 2420/02 (2013.01); A61L 2430/06 (2013.01); A61L 2430/20 (2013.01);
Abstract

The invention relates to a method for producing a bioartificial and primarily acellular fibrin-based construct, wherein a mixture of cell-free compositions containing fibrinogen and thrombin is applied to a surface and subsequently pressurised. An additional aspect of the invention is directed to such fibrin-based bioartificial acellular constructs obtained according to the invention, with improved biomechanical properties, as well as to the use of same in the field of implantology, cartilage replacement or tissue replacement.


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