The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2024
Filed:
Jul. 29, 2019
Applicants:
Sarepta Therapeutics, Inc., Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Justin Wolfe, Cambridge, MA (US);
Colin M. Fadzen, Cambridge, MA (US);
Bradley L. Pentelute, Cambridge, MA (US);
Gunnar J. Hanson, Cambridge, MA (US);
Assignees:
Sarepta Therapeutics, Inc., Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/64 (2017.01); A61K 47/54 (2017.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 47/6455 (2017.08); A61K 47/549 (2017.08); C12N 15/113 (2013.01); C12N 2310/11 (2013.01); C12N 2310/3233 (2013.01); C12N 2310/3513 (2013.01);
Abstract
Provided herein are oligonucleotides, trimeric peptides, and peptide-oligonucleotide-conjugates. Also provided herein are methods of treating a muscle disease in a subject in need thereof, comprising administering to the subject oligonucleotides, trimeric peptides, and peptide-oligonucleotide-conjugates described herein.