The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2024
Filed:
Apr. 26, 2019
Applicant:
Children's National Medical Center, Washington, DC (US);
Inventors:
Michael Keller, Laurel, MD (US);
Catherine Bollard, Bethesda, MD (US);
Patrick Hanley, Washington, DC (US);
Conrad Russell Cruz, Bethesda, MD (US);
Haili Lang, Derwood, MD (US);
Shabnum Patel, Washington, DC (US);
Assignee:
Children's National Medical Center, Washington, DC (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/04 (2006.01); A61P 31/06 (2006.01); C12N 5/0783 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/04 (2013.01); A61P 31/06 (2018.01); C12N 5/0636 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/70 (2013.01); C12N 2501/2304 (2013.01); C12N 2501/2307 (2013.01); C12N 2501/2315 (2013.01); C12N 2501/2321 (2013.01); C12N 2501/24 (2013.01); C12N 2501/25 (2013.01);
Abstract
The present disclosure relates, at least in part, to mycobacterial polynucleotides and polypeptides, to fragments or variants thereof, to cells comprising the mycobacterial polynucleotides and polypeptides, to cells comprising the mycobacterial polynucleotides and polypeptides, that are engineered to expand T-cells ex vivo, and to methods of use thereof.