The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 2024
Filed:
Sep. 21, 2018
Applicant:
University of Miami, Miami, FL (US);
Inventors:
Joshua M. Hare, Miami Beach, FL (US);
Konstantinos Chatzistergos, Miami, FL (US);
Assignee:
UNIVERSITY OF MIAMI, Miami, FL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/34 (2015.01); A61K 38/25 (2006.01); C12N 1/38 (2006.01); C12N 5/074 (2010.01); C12N 5/077 (2010.01); C12N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 35/34 (2013.01); A61K 38/25 (2013.01); C12N 1/38 (2013.01); C12N 5/0657 (2013.01); C12N 5/0696 (2013.01); C12N 5/10 (2013.01); C12N 2501/415 (2013.01); C12N 2501/60 (2013.01); C12N 2501/85 (2013.01); C12N 2506/45 (2013.01);
Abstract
The disclosure provides a method of obtaining a population of cardiomyogenic precursor cells. The method comprises (a) differentiating induced pluripotent stem cells (iPSCs) to iPSC-derived cardiac precursor cells; and (b) isolating cardiac precursor cells expressing mammalian growth hormone-releasing hormone receptor (GHRHR) to obtain a population of iPSC-derived cardiomyogenic precursor cells.