The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2024
Filed:
May. 07, 2021
Applicant:
Washington University, St. Louis, MO (US);
Inventors:
Jieya Shao, St. Louis, MO (US);
Marc Diamond, St. Louis, MO (US);
Assignee:
Washington University, St. Louis, MO (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); C07K 16/40 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57496 (2013.01); C07K 16/40 (2013.01); C12Y 306/04006 (2013.01); G01N 33/5088 (2013.01); C07K 2317/565 (2013.01); G01N 2333/914 (2013.01); G01N 2440/14 (2013.01);
Abstract
The present disclosure provides methods to quantify VCP phosphorylation at specific amino acid residue to predict responsiveness of a subject having a cancer or tumor to a genotoxic treatment, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions.