The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2024

Filed:

May. 03, 2024
Applicant:

Dna Script, Le Kremlin-Bicêtre, FR;

Inventors:

Ilya Aparin, Le Kremlin-Bicêtre, FR;

Mikhael Soskine, Le Kremlin-Bicêtre, FR;

Weidong Wu, Le Kremlin-Bicêtre, FR;

Adeline Veillet, Le Kremlin-Bicêtre, FR;

Assignee:

DNA SCRIPT, Le Kremlin-Bicêtre, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C07F 9/38 (2006.01); C12N 9/12 (2006.01); C12N 15/10 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C12P 19/34 (2013.01); C07F 9/3847 (2013.01); C12N 9/1264 (2013.01); C12N 15/1096 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6869 (2013.01);
Abstract

This disclosure relates to an enzymatic method of synthesizing a polynucleotide, comprising a deprotecting step which uses as a deprotecting agent a specific phosphonate compound. It also pertains to a method for deprotecting 3'-O-amino elongated fragments of a polynucleotide in an enzymatic method of synthesizing a polynucleotide, comprising contacting the elongated fragments with this phosphonate compound. This disclosure further relates to a kit for synthesizing a polynucleotide comprising one or more vials of synthesis reagents, at least one of which contains an effective amount of a phosphonate compound and to a specific method for preparing said phosphonate compound.


Find Patent Forward Citations

Loading…