The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2024
Filed:
Mar. 01, 2019
Applicant:
Allogene Therapeutics, Inc., South San Francisco, CA (US);
Inventors:
Andrew Ross Nager, Mountain View, CA (US);
Spencer Park, Belmont, CA (US);
Javier Fernando Chaparro Riggers, San Mateo, CA (US);
Regina Junhui Lin, San Mateo, CA (US);
Thomas John Van Blarcom, Oakland, CA (US);
Assignee:
Allogene Therapeutics, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/90 (2006.01); A61K 35/17 (2015.01); A61K 45/06 (2006.01); C07K 14/705 (2006.01); C07K 14/71 (2006.01); C07K 14/715 (2006.01); C07K 14/72 (2006.01); C12N 5/0783 (2010.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/90 (2013.01); A61K 35/17 (2013.01); A61K 45/06 (2013.01); C07K 14/70517 (2013.01); C07K 14/70578 (2013.01); C07K 14/71 (2013.01); C07K 14/715 (2013.01); C07K 14/7155 (2013.01); C07K 14/7156 (2013.01); C07K 14/72 (2013.01); C12N 5/0636 (2013.01); C12Y 502/01008 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/70 (2013.01);
Abstract
The present invention provides inducible chimeric cytokine receptors responsive to a ligand, e.g., a small molecule or protein, uses of such receptors for improving the functional activities of genetically modified immune cells, such as T cells, comprising the inducible chimeric cytokine receptors, and compositions comprising such cells.