The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2024

Filed:

Jun. 25, 2019
Applicant:

Yipcell Inc., Seoul, KR;

Inventors:

Ji Hyeon Ju, Seoul, KR;

Yoo Jun Nam, Bucheon-si, KR;

Ye Ri Rim, Seoul, KR;

Assignee:

YiPCELL Inc., Seoul, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); A61K 31/70 (2006.01); A61K 31/728 (2006.01); A61K 35/32 (2015.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0655 (2013.01); A61K 31/728 (2013.01); A61K 35/32 (2013.01); C12N 2500/99 (2013.01); C12N 2501/15 (2013.01); C12N 2501/155 (2013.01);
Abstract

A method for preparing chondrocyte pellets including: (a) culturing human induced pluripotent stem cells so as to form and obtain embryoid bodies; (b) inducing the embryonic bodies obtained in step (a) to become outgrowth cells and isolating same; and (c) culturing the outgrowth cells isolated in step (b) in a pellet form. A pharmaceutical composition including the chondrocyte pellets prepared by the preparation method; or a method for preventing or treating arthritis, including administering the chondrocyte pellets prepared by the method to an arthritis patient. Chondrocyte pellets of the present invention have a remarkably high rate of differentiation into chondrocytes, uniform size, and a homogeneous differentiation degree, and a pharmaceutical composition, including the pellets, has excellent cartilage regeneration effects at the site of cartilage damage, and is in injectable form, which does not require surgery, such that pain is relieved and a continuous arthritis treatment is provided.


Find Patent Forward Citations

Loading…