The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2024
Filed:
Nov. 10, 2020
Applicant:
Lonza Walkersville, Inc., Walkersville, MD (US);
Inventors:
Matthew Hewitt, Walkersville, MD (US);
Eytan Abraham, Walkersville, MD (US);
Nicholas Ostrout, Walkersville, MD (US);
Assignee:
LONZA WALKERSVILLE, INC., Walkersville, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C12N 5/0636 (2013.01); C12N 2501/51 (2013.01); C12N 2501/515 (2013.01); C12N 2502/1121 (2013.01); C12N 2502/1157 (2013.01);
Abstract
The present disclosure provides methods for assessing and optimizing cellular quality of a cell-based therapy that is being produced in an automated cell engineering system. The methods suitably include monitoring molecular characteristics of the cells before, during, and after the automated process to provide feedback to the process parameters. In embodiments, the cells being produced are Chimeric Antigen Receptor (CAR) T-cells.