The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2024
Filed:
Jan. 31, 2023
Applicant:
Purdue Research Foundation, West Lafayette, IN (US);
Inventors:
Casey J. Krusemark, West Lafayette, IN (US);
Emily C. Dykhuizen, West Lafayette, IN (US);
Sijie Wang, Lafayette, IN (US);
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/10 (2006.01); A61P 35/02 (2006.01); C07K 5/107 (2006.01); C07K 7/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61P 35/02 (2018.01); C07K 5/1016 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to series of peptidomimetic compounds selectively targeting CBX8 of polycomb chromobox protein homolog proteins. Pharmaceutical compositions of those compounds and methods of using them in the treatment of diseases involved CBX8 pharmacology, including various cancers and leukemia, by administering therapeutically effective amounts of such compound alone or together with other therapeutics, are within the scope of this disclosure.