The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2024

Filed:

Jul. 15, 2021
Applicant:

Janssen Biotech, Inc., Horsham, PA (US);

Inventors:

Zemeda Ainekulu, San Diego, CA (US);

Qiang Chen, San Diego, CA (US);

Ellen Chi, Del Mar, CA (US);

Wilson Edwards, Cardiff by the Sea, CA (US);

Matt Husovsky, Ramona, CA (US);

Ann Lacombe, San Diego, CA (US);

Quynh Nguyen, San Diego, CA (US);

Paul H. Kim, Encinitas, CA (US);

H. Mimi Zhou, San Diego, CA (US);

John T. Lee, Ambler, PA (US);

Assignee:

Janssen Biotech, Inc., Horsham, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C07H 21/04 (2006.01); C07K 1/22 (2006.01); C07K 16/42 (2006.01); C12N 5/02 (2006.01); C12N 15/00 (2006.01); C12P 21/06 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/4241 (2013.01); C07K 1/22 (2013.01); G01N 33/6854 (2013.01); C07K 2317/20 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01);
Abstract

In certain aspects, the disclosure relates to anti-idiotype antibodies and antigen-binding portions thereof that specifically bind a KL2B413 containing protein, e.g., an antibody or antigen-binding portions thereof. In some aspects, the anti-idiotype antibodies and antigen-binding portions of the present disclosure can be used in methods to detect and quantify cells expressing chimeric antigen receptors that include KL2B413.


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