The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2024
Filed:
Feb. 08, 2021
Board of Trustees of Southern Illinois University, Carbondale, IL (US);
Debashree Mukherjea, Springfield, IL (US);
Vickram Ramkumar, Springfield, IL (US);
Leonard Rybak, St. Louis, MO (US);
Board of Trustees of Southern Illinois University, Carbondale, IL (US);
Abstract
Compositions and treatment regimen that includes the compositions, suitable for preventing, treating and restoring hearing acuity in a subject are provided. The treatment regimen includes an amount of capsaicin and an amount of a TNF-α inhibitor (such as etanercept) that are delivered relatively simultaneously to a subject. Methods of providing a pretreatment to a subject suitable for preventing hearing loss are also provided. The capsaicin and TNFα inhibitor may be provided in different delivery forms to the subject. Methods of providing a treatment for hearing loss with a TNFα inhibitor alone, such as entanercept, or with capsaicin alone, are also provided.