The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2024
Filed:
Jan. 05, 2018
Netris Pharma, Lyons, FR;
Universite Claude Bernard Lyon 1, Villeurbanne, FR;
Centre National DE LA Recherche Scientifique, Paris, FR;
Centre Léon-bérard, Lyons, FR;
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Benjamin Ducarouge, La Tour du Pin, FR;
David Goldschneider, Villeurbanne, FR;
Anna Maria Rita Redavid, Rutigliano, IT;
Benjamin Gibert, Villeurbanne, FR;
Patrick Mehlen, Serezin-de-la-Tour, FR;
Netris Pharma, Lyons, FR;
Université Claude Bernard Lyon 1, Villeurbanne, FR;
Centre national de la Recherche Scientifique, Paris, FR;
Centre Léon-Bérard, Lyons, FR;
Institut National de la Sante et de la Recherche Medicale, Paris, FR;
Abstract
The invention is the combination or combined use of (i) a compound able to disrupt or impede netrin-1/netrin-1 receptors interaction or netrin-1-mediated receptor dimerization, also called herein a NTN1 neutralizing agent, which compound may be an antibody binding to netrin-1 or anti-netrin-1 antibody, and (ii) an immune checkpoint inhibitor, in the treatment of cancer. The composition may comprise an anti-netrin-1 antibody and an immune checkpoint inhibitor, for use as an anticancerous drug with a simultaneous, separate or sequential administration of the anti-netrin-1 antibody and the immune checkpoint inhibitor to a patient.