The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2024

Filed:

Jun. 23, 2022
Applicant:

Drexel University, Philadelphia, PA (US);

Inventors:

Sandhya Kortagere, Newtown, PA (US);

Andreia C. K. Mortensen, Narbeth, PA (US);

Ole V. Mortensen, Narbeth, PA (US);

Joseph M. Salvino, Chester Springs, PA (US);

Assignee:

Drexel University, Philadelphia, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61P 25/28 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61P 25/28 (2018.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 405/14 (2013.01);
Abstract

The present invention provides compounds useful for treating, ameliorating or preventing a disease or disorder that is caused, induced or characterized by abnormal reduction in glutamate transporter activity or abnormal increase in extracellular CNS glutamate concentration in a subject. In certain embodiments, the compound stimulates a glutamate transporter.


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