The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2024
Filed:
Jan. 19, 2023
Applicant:
Ikena Oncology, Inc., Boston, MA (US);
Inventors:
Alfredo C. Castro, Somerville, MA (US);
James Martin Nolan, III, Boston, MA (US);
Sarah Jean Bethune, Durham, NC (US);
Corinne Marie Folberth, Durham, NC (US);
Assignee:
Ikena Oncology, Inc., Boston, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/53 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention provides freebase and salt forms of (R)-N-(2-(5-fluoropyridin-3-yl)-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-amine, which act as inhibitors of AHR, and compositions and methods thereof, useful for treating various conditions in which the aryl hydrocarbon receptor (AHR) is implicated.