The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2024
Filed:
Nov. 12, 2018
Tarapeutics Science Inc., Bengbu, CN;
Jing Liu, Anhui, CN;
Qingsong Liu, Anhui, CN;
Xuesong Liu, Anhui, CN;
Beilei Wang, Anhui, CN;
Cheng Chen, Anhui, CN;
Ziping Qi, Anhui, CN;
Wenchao Wang, Anhui, CN;
Junjie Wang, Anhui, CN;
Zongru Jiang, Anhui, CN;
Wenliang Wang, Anhui, CN;
Shuang Qi, Anhui, CN;
Li Wang, Anhui, CN;
Tarapeutics Science Inc., Bengbu, CN;
Abstract
Described herein is a kinase inhibitor compound represented by formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug of the compound. Further described herein is a pharmaceutical composition containing the kinase inhibitor compound, as well as methods of using the compound to inhibit cKIT (especially mutant cKIT/T670I), FLT3 (comprising mutant FLT3-ITD), PDGFRα, PDGFRβ, and/or VEGFR2 kinase activity in cells or a subject, and methods for preventing or treating disorders related to cKIT (especially mutant cKIT/T670I), FLT3 (comprising mutant FLT3-ITD), PDGFRα, PDGFRβ, and/or VEGFR2 activity in a subject.