The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2024

Filed:

Mar. 25, 2020
Applicant:

Evonik Operations Gmbh, Essen, DE;

Inventors:

Timo Stahl, Limeshain, DE;

Axel Ronneburg, Hanau, DE;

Imad Moussallem, Hanau, DE;

Juliette Halli, Frankfurt am Main, DE;

Petra Picha, Friedrichsdorf, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 51/08 (2006.01); C07D 301/12 (2006.01);
U.S. Cl.
CPC ...
C07C 51/08 (2013.01); C07D 301/12 (2013.01);
Abstract

The present invention pertains to a process for preparing 3-hydroxy-3-methylbutyric acid (HMB) or a salt thereof, the method comprising (a) reacting isobutylene oxide with cyanide in order to obtain 3-hydroxy-3-methylbutyronitrile, and (b) hydrolyzing the 3-hydroxy-3-methylbutyronitrile obtained in step (a) in order to obtain HMB, wherein hydrolysis step (b) is performed using either at least one nitrilase enzyme or, alternatively, using a combination of enzymes, said combination comprising at least one nitrile hydratase and at least one amidase.


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Stahl, Timo. (2024). Process for preparing 3-hydroxy-3-methylbutyric acid (hmb) and salts thereof (U.S. Patent No. 12162828). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12162828

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