The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2024

Filed:

Mar. 27, 2020
Applicant:

Taiwanj Pharmaceuticals Co., Ltd., Zhubei, TW;

Inventors:

Syaulan S. Yang, Zhubei, TW;

Yan-feng Jiang, Kaohsiung, TW;

Meng-hsien Liu, Toufen, TW;

Chia-hao Chang, New Taipei, TW;

Hao Shiuan Liu, Taichung, TW;

Ying-chu Shih, Zhubei, TW;

Sheng Hung Liu, Zhubei, TW;

Chiung Wen Wang, Zhubei, TW;

Ting-ni Huang, Taipei, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/14 (2006.01); C07C 233/42 (2006.01); C07C 235/38 (2006.01); C07C 259/06 (2006.01); C07C 311/20 (2006.01); C07D 233/74 (2006.01);
U.S. Cl.
CPC ...
C07C 233/42 (2013.01); C07C 235/38 (2013.01); C07C 259/06 (2013.01); C07C 311/20 (2013.01); C07D 209/14 (2013.01); C07D 233/74 (2013.01);
Abstract

The compounds represented by Formula (I), which are peripheral alkyl and alkenyl chains extended benzene derivatives, are useful as dual autotaxin (ATX)/histone deacetylase (HD AC) inhibitors. These compounds may be included in a pharmaceutical composition along with a pharmaceutically acceptable carrier, and be used in a therapeutically effective amount for prophylaxis or treatment of various diseases and disorders.


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