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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12162818 B1

PDFFull Text
Date of Patent:
Dec. 10, 2024

Filed:

Jan. 13, 2022

Inhibitors of the n-terminal domain of the androgen receptor

Applicants:

The Regents of the University of California, Oakland, CA (US);

The United States Government Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Matthew Rettig, Los Angeles, CA (US);

Michael E. Jung, Los Angeles, CA (US);

D. Elshan Nakath G. Ralalage, Los Angeles, CA (US);

Jiabin An, Los Angeles, CA (US);

Assignees:

The Regents of the University of California, Oakland, CA (US);

The United States Government represented by the Department of Veterans Affairs, Washington, DC (US);

Attorneys:

Foley Hoag LLP

David P. Halstead

Primary Examiner:

Brian E McDowell

Int. Cl.
CPC ...
C07C 225/16 (2006.01); A61P 35/00 (2006.01); C07C 33/48 (2006.01); C07C 49/223 (2006.01); C07C 235/34 (2006.01); C07C 235/78 (2006.01); C07C 321/20 (2006.01); C07D 207/08 (2006.01); C07D 211/32 (2006.01); C07D 241/04 (2006.01); C07D 265/30 (2006.01); C07D 303/32 (2006.01); C07D 303/40 (2006.01); C07D 307/52 (2006.01); C07D 333/24 (2006.01);
U.S. Cl.
CPC ...
C07C 225/16 (2013.01); A61P 35/00 (2018.01); C07C 33/486 (2013.01); C07C 49/223 (2013.01); C07C 235/34 (2013.01); C07C 235/78 (2013.01); C07C 321/20 (2013.01); C07D 207/08 (2013.01); C07D 211/32 (2013.01); C07D 241/04 (2013.01); C07D 265/30 (2013.01); C07D 303/32 (2013.01); C07D 303/40 (2013.01); C07D 307/52 (2013.01); C07D 333/24 (2013.01);
Abstract

The present disclosure provides compounds of Formula (VIIb) and methods for inhibiting or degrading the N-terminal domain of the androgen receptor, as well as methods for treating cancers such as prostate cancer.

Find Patent Forward Citations

Quick Actions:

Rettig, Matthew. (2024). Inhibitors of the n-terminal domain of the androgen receptor (U.S. Patent No. 12162818). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12162818

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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