The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2024

Filed:

May. 25, 2023
Applicant:

The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, CN;

Inventors:

Zhihao Zha, Guangzhou, CN;

Xiangsong Zhang, Guangzhou, CN;

Renbo Wu, Guangzhou, CN;

Jianbo Liu, Guangzhou, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07B 59/002 (2013.01);
Abstract

An F-18 labeled chiral pure derivative of hydroxyfuran, a preparation method and use thereof were provided. (4R, 5R)[F]FAA provided by the present disclosure is a chiral pure radioactive compound, and three other chiral pure [F]FAA structural formulae are also provided by the present disclosure. The present disclosure provides a chiral pure radioactive probe (4R, 5R)[F]FAA, which shows unique tumor diagnostic efficiency and similar distribution to AA, and can be used for early diagnosis of tumors, pathological studies, assessment of disease progression, and evaluation for efficacy.


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