The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2024

Filed:

Oct. 12, 2021
Applicants:

Bio-rad Europe Gmbh, Basel, CH;

Bio-rad Laboratories, Inc., Hercules, CA (US);

Inventors:

Kalyan Handique, Ann Arbor, MI (US);

Ronald Lebofsky, Richmond, CA (US);

Emilie Celine Claudie Macke, Caestre, FR;

Rebecca Dievart, Armentieres, FR;

Christophe Quiring, Hazebrouck, FR;

Sophie Pierre, Chatou, FR;

Assignees:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Bio-Rad Europe GmbH, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/50855 (2013.01); B01L 3/50853 (2013.01); B01L 2200/0684 (2013.01); B01L 2300/042 (2013.01); B01L 2300/069 (2013.01); B01L 2300/123 (2013.01); B01L 2300/14 (2013.01);
Abstract

A system, method, and platform for target detection, the system including: a base substrate; a set of sample processing regions defined at a broad surface of the substrate, wherein each of the set of sample processing regions includes: a set of microwell subarrays arranged in a gradient between an upstream end and a downstream end of each respective sample processing region, and a boundary separating each respective sample processing region from adjacent sample processing regions; and a cover substrate configured to mate with the base substrate in a coupled mode, the cover substrate comprising a network of venting channels aligned with the set of sample processing regions upon mating the base substrate with the cover substrate in the coupled mode, the network of venting channels providing gas exchange between the base substrate and an environment surrounding the microwell assembly. The invention(s) can be used for MPN assays.


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