The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2024
Filed:
May. 30, 2023
Applicant:
Korea University Research and Business Foundation, Seoul, KR;
Inventors:
Young-Keun Kim, Seoul, KR;
Heemin Kang, Seoul, KR;
Min-Jun Ko, Seoul, KR;
Gunhyu Bae, Hwaseong-si, KR;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0786 (2010.01); A61K 9/51 (2006.01); A61K 47/69 (2017.01); A61N 2/00 (2006.01); C12N 13/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5115 (2013.01); A61K 9/5123 (2013.01); A61K 47/6929 (2017.08); A61N 2/00 (2013.01); C12N 5/0645 (2013.01); C12N 13/00 (2013.01); A61N 2/002 (2013.01);
Abstract
The present invention relates to a nanohelix-substrate complex for controlling adhesion and polarization of macrophages, a manufacturing method thereof, and a method of controlling adhesion and polarization of macrophages by using the nanohelix-substrate complex, and the method of controlling adhesion and polarization of macrophages may temporally and reversibly control adhesion and phenotypic polarization of macrophages in vivo and ex vivo by controlling application/non-application of a magnetic field to the nanohelix-substrate complex.