The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2024
Filed:
Aug. 26, 2019
Applicant:
North Carolina State University, Raleigh, NC (US);
Inventors:
Assignee:
NORTH CAROLINA STATE UNIVERSITY, Raleigh, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61M 37/00 (2006.01); C08F 220/34 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0021 (2013.01); A61M 37/0015 (2013.01); C08F 220/34 (2013.01); A61M 2037/0061 (2013.01);
Abstract
Disclosed are compositions and methods for microneedle patches comprising copolymer designed for glucose triggered insulin delivery. In one aspect, disclosed herein are microneedle patches comprising insulin loaded copolymers; wherein the insulin dissociates from the microneedle in an hyperglycemic environment; wherein the copolymer comprises poly(N-vinylpyrrolidone-co-2-N(dimethylamino)ethyl acrylate-co-3-(acrylamido)phenylboronic acid and methods of their use.