The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2024
Filed:
May. 04, 2022
Applicant:
Janux Therapeutics, Inc., San Diego, CA (US);
Inventors:
David Campbell, San Diego, CA (US);
Thomas R. Diraimondo, San Diego, CA (US);
Ramesh Bhatt, San Diego, CA (US);
Assignee:
JANUX THERAPEUTICS, INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
A61K 47/6849 (2017.08); A61K 47/6843 (2017.08); A61K 47/6851 (2017.08); A61K 47/6871 (2017.08); A61K 47/6889 (2017.08);
Abstract
Provided herein are multispecific antibodies for redirecting T cells to cancers, that rely on binding of one antigen interacting portion of the antibody to a tumor-associated antigen or marker, such as epidermal growth factor receptor (EGFR), while a second antigen interacting portion can bind to an effector cell antigen on a T cell, such as CD3, pharmaceutical compositions thereof, as well as nucleic acids, and methods for making and discovering the same.