The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2024

Filed:

Oct. 28, 2022
Applicant:

Proabtech Inc., Gwangju, KR;

Inventors:

Jeong Haeng Cho, Gyeonggi-do, KR;

Sun Oh Shin, Gwangju, KR;

Hyun Woo Kim, Seoul, KR;

Hyeongseok Kim, Seoul, KR;

Dong Ho Bak, Jeollabuk-do, KR;

Inchan Kwon, Gwangju, KR;

Byungseop Yang, Seoul, KR;

Assignee:

Proabtech Inc., Gwangju, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/44 (2006.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); A61K 47/64 (2017.01); A61P 19/06 (2006.01); C12N 9/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/44 (2013.01); A61K 47/545 (2017.08); A61K 47/60 (2017.08); A61K 47/643 (2017.08); A61P 19/06 (2018.01); C12N 9/0048 (2013.01); C12Y 107/03003 (2013.01);
Abstract

The present specification discloses a urate oxidase-albumin conjugate, a preparation method thereof, a urate oxidase variant contained in the urate oxidase-albumin conjugate, and a preparation method thereof. The urate oxidase-albumin conjugate is characterized in that three or more albumins are conjugated to the urate oxidase variant through a linker, thereby improving half-life and reducing immunogenicity. In addition, the urate oxidase-albumin conjugate can be used to prevent or treat various diseases, disorders and/or indications caused by uric acid.


Find Patent Forward Citations

Loading…