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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12161673 B1

PDFFull Text
Date of Patent:
Dec. 10, 2024

Filed:

Sep. 13, 2023

Mage-a4 peptide dual t cell engagers

Applicant:

Cdr-life Ag, Schlieren, CH;

Inventors:

Stephanie Jungmichel, Zürich, CH;

Fabian Bert Scheifele, Mägenwil-Aargau, CH;

Anna Maria Sobieraj, Zürich, CH;

Philipp Robert Richle, Zürich, CH;

Hannes Merten, Zürich, CH;

Leonardo Borras, Birmensdorf, CH;

Christian Valdemar Vinge Leisner, Thalwil, CH;

Assignee:

CDR-LIFE AG, Horgen, CH;

Attorneys:

LATHROP GPM LLP

James H. Velema, Esq.

Michael J. Spellberg, Esq.

Primary Examiner:

Hong Sang

Int. Cl.
CPC ...
C07K 16/30 (2006.01); A61K 35/17 (2015.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/38 (2006.01); C12N 15/63 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 39/4611 (2023.05); A61K 39/4631 (2023.05); A61K 39/464499 (2023.05); C07K 16/30 (2013.01); C12N 15/63 (2013.01); A61K 2239/29 (2023.05); A61K 2239/57 (2023.05); C07K 16/2809 (2013.01); C07K 16/2833 (2013.01); C07K 2317/622 (2013.01);
Abstract

Described herein are antigen binding proteins with specificity to Melanoma-Associated Antigen A4 (MAGE-A4) peptide-MHC (pMHC). Also described are multispecific antigen binding proteins comprising an antigen binding domain with specificity to CD3, and at least one MAGE-A4 pMHC antigen binding domain. Methods of treating cancer with the same are also described.

Find Patent Forward Citations

Jungmichel, Stephanie. (2024). Mage-a4 peptide dual t cell engagers (U.S. Patent No. 12161673). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12161673

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