The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2024

Filed:

Jun. 21, 2019
Applicant:

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Inventors:

Nathanael S. Gray, Boston, MA (US);

Jaebong Jang, Boston, MA (US);

Dries De Clercq, Wetteren, BE;

David A. Scott, Boston, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 243/14 (2006.01); A61K 9/00 (2006.01); A61K 31/5513 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5513 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 243/14 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); A61K 9/0012 (2013.01);
Abstract

The application relates to compounds, or pharmaceutically acceptable salts, hydrates, solvates, or stereoisomers thereof, which modulate the activity of EGFR, a pharmaceutical composition comprising said compounds, and methods of treating or preventing a disease in which EGFR plays a role.


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