The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 2024

Filed:

Feb. 22, 2021
Applicant:

Ohio State Innovation Foundation, Columbus, OH (US);

Inventors:

Wolfgang Sadee, Upper Arlington, OH (US);

John Oberdick, Columbus, OH (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/485 (2006.01); A61K 31/4178 (2006.01); A61K 45/06 (2006.01); A61P 25/36 (2006.01);
U.S. Cl.
CPC ...
A61K 31/485 (2013.01); A61K 31/4178 (2013.01); A61K 45/06 (2013.01); A61P 25/36 (2018.01);
Abstract

Disclosed is a method for reducing or preventing fetal opioid dependence in a drug dependent or opioid tolerant pregnant subject. The method involves administering to the pregnant subject a composition comprising an opioid antagonist in an amount effective to reduce or prevent fetal opioid dependence, wherein the opioid antagonist a) is orally available or delivered systemically and reaches the circulation of the pregnant subject, b) is substantially excluded from the subject's brain by the blood brain barrier, and c) penetrates the placenta and enters the fetal brain. The method also includes administering the opioid antagonist to the neonate in increasing amounts to facilitate weaning the neonate from continued opioid maintenance.


Find Patent Forward Citations

Sadee, Wolfgang. (2024). Treatments and prevention of opioid neonatal abstinence syndrome (U.S. Patent No. 12161641). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12161641

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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