The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2024

Filed:

Aug. 07, 2017
Applicant:

Duke University, Durham, NC (US);

Inventors:

Luigi Racioppi, Durham, NC (US);

Erik Nelson, Durham, NC (US);

Wei Huang, Durham, NC (US);

Nelson Chao, Durham, NC (US);

Donald McDonnell, Durham, NC (US);

Assignee:

Duke University, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 35/17 (2015.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); G01N 33/569 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56972 (2013.01); A61K 35/17 (2013.01); A61K 39/001129 (2018.08); A61P 35/00 (2018.01); G01N 33/57415 (2013.01); A61K 38/00 (2013.01); G01N 2800/50 (2013.01);
Abstract

Provided herein are compositions including a CaMKK2 inhibitor and an anti-cancer therapeutic agent and methods of treating cancer in a subject by administering a therapeutically effective amount of the composition to a subject. The subject may be selected for treatment based on an immune cell measurement of a sample from the subject. Methods of treating cancer by administering a therapeutically effective amount of a CaMKK2 inhibitor, and administering a therapeutically effective amount of an anti-cancer therapeutic agent to the subject are also provided. Kits including combination of a CaMKK2 inhibitor and another anti-cancer therapeutic agent are also provided.


Find Patent Forward Citations

Loading…