The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2024
Filed:
Dec. 05, 2022
Applicant:
Northeastern University, Boston, MA (US);
Inventors:
Shashi K. Murthy, Newton, MA (US);
Bradley B. Collier, Jamaica Plain, MA (US);
Assignee:
Northeastern University, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0784 (2010.01); C07K 14/525 (2006.01); C07K 14/535 (2006.01); C07K 14/54 (2006.01); C07K 14/545 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 1/22 (2006.01); C12M 3/00 (2006.01); C12M 3/06 (2006.01); C12N 5/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0639 (2013.01); C07K 14/525 (2013.01); C07K 14/535 (2013.01); C07K 14/5406 (2013.01); C07K 14/5412 (2013.01); C07K 14/545 (2013.01); C12M 1/22 (2013.01); C12M 23/16 (2013.01); C12M 23/42 (2013.01); C12M 25/02 (2013.01); C12M 29/10 (2013.01); C12M 41/14 (2013.01); C12N 5/0018 (2013.01); A61K 39/00 (2013.01);
Abstract
Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease.