The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2024
Filed:
Sep. 08, 2022
Applicant:
Howard Hughes Medical Institute, Chevy Chase, MD (US);
Inventors:
Luke D. Lavis, Ashburn, VA (US);
Claire Deo, Heidelberg, DE;
Assignee:
HOWARD HUGHES MEDICAL INSTITUTE, Chevy Chase, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
C07F 7/08 (2006.01); C07D 405/04 (2006.01); C07D 405/14 (2006.01); G01N 21/78 (2006.01);
U.S. Cl.
CPC ...
C07F 7/0816 (2013.01); C07D 405/04 (2013.01); C07D 405/14 (2013.01); G01N 21/78 (2013.01);
Abstract
The presently-disclosed subject matter includes fluorescent indicators, including bright and targetable red Ca2+ indicators. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance. Fluorescent indicators of the presently-disclosed subject matter include a compound of the formula: